Cook the Meat: In a skillet, brown ground beef and sausage over medium heat. Drain fat and set aside. Preheat oven to 425°F (220°C).
Assemble the Pie: Roll out one pie crust into a deep-dish pie pan. Layer with half the mozzarella, then add the beef, sausage, and pepperoni.
Sauce & Season: Pour pizza sauce over the meat, then sprinkle with Italian seasoning, garlic powder, and red pepper flakes.
Cheese Layers: Add remaining mozzarella and cheddar/provolone, followed by extra pepperoni slices. Place second pie crust on top, sealing edges, and brush with melted butter.
Bake: Bake for 20-25 minutes, until the crust is golden and cheese is bubbling. Let cool slightly, then slice.
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